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Immunology
(Cezmi Akdis)

Dermatology
(Mübeccel Akdis)

Molecular Allergology
(Katja Bärenfaller)

Molecular Allergology
(Reto Crameri)

Molecular Immunology
(Liam O‘Mahony)

Vaccine Development
(Claudio Rhyner)

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WIRM

Head: Liam O‘Mahony
Degree: PD, Ph.D.


Phone: +41 (0) 81 410 08 53
E-mail: liam.omahony(a)siaf.uzh.ch

Group members:
  1. Weronika Barcik
  2. Ruth Ferstl
  3. Remo Frei
  4. Marcin Wawrzyniak

Molecular Immunology

Molecular Immunology

The immune response is a tightly regulated process which normally results in protection from infection and tolerance of innocuous environmental antigens.  However, in allergic disease, the activated immune response results in a chronic pro-inflammatory state characterized by antibody secretion (IgE) and T cell activation to normally well-tolerated antigens.  The role played by microbial and allergen activated dendritic cells in these phenomena is not well understood in allergic patients. 

Our group is examining the molecular mechanisms and clinical importance of Toll-like Receptors (TLRs) and C-type Lectin Receptors (CLRs) activation by microbial components in dendritic cells from patients with allergy and asthma.

Publications

Pubmed search